Approximately 15 to 20 of the Cape Cod Healthcare patients have been prescribed the new (soon to be blockbuster) drug Sovaldi (Sofosbuvir) which was released by Gilead (I am still kicking myself for not buying shares at $60) and received US Food and Drug Administration (FDA) approval in 2013. Sofosbuvir is used to treat infection of hepatitis C virus (HCV) and has a very high cure rate. It acts to inhibit the viral RNA polymerase, which is a viral protein that replicates the viral genome. Without an active viral RNA polymerase, the virus cannot replicate.
|Sofosbuvir (looks a little like a Twinkie) - Photo: Andrew Karpenko, University of Washington|
One problem with Sofosbuvir is that it is prohibitively expensive. Stupidly expensive. Insanely expensive.
There has been some discussion about trying to get the cost of Sovaldi down. Hopefully, some funding for public health programs geared toward younger adults and heroin use/HCV infection happen soon. To have an uptick in heroin use and HCV infection after years of a downward trend would erase years of progress.
- Lance D. Presser has a PhD in microbiology and immunology and is a public health laboratorian.
- Hire Lance for any of your microbiology, virology, teaching, editing, grant writing, or public health consulting needs.
- Follow Lance @ldpsci